Network analysis

We have pioneered network analysis of foraging basidiomycete fungi growing in unconstrained microcosms (Bebber et al. 2007a; Bebber et al. 2007b; Boddy et al. 2009; Boddy et al. 2010; Fricker et al. 2008a; Fricker et al. 2007; Fricker et al. 2008b; Heaton et al. 2010; Rotheray et al. 2008). We have shown using graph-theoretic analysis…

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Imaging glutathione levels in vivo

We developed a system for quantitative imaging of total cytoplasmic glutathione (GSH) in vivo following GST-catalysed conjugation to monochlorobimane (MCB) to give a fluorescent glutathione-bimane (GSB) adduct. This has allowed measurement of concentrations of GSH in defined cell types in intact tissues, to dissect the control of GSH synthesis and to analyse activities of GSH-based…

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